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Article

Involvement of PPAR nuclear receptors in tissue injury and wound repair

1 Mar 2006

Abstract excerpt

Tissue damage resulting from chemical, mechanical, and biological injury, or from interrupted blood flow and reperfusion, is often life threatening. The subsequent tissue response involves an intricate series of events including inflammation, oxidative stress, immune cell recruitment, and cell survival, proliferation, migration, and differentiation. In addition, fibrotic repair characterized by myofibroblast...

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PMID: 16511592
DOI: 10.1172/jci27958

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