Article
Effects of PGF2alpha on human melanocytes and regulation of the FP receptor by ultraviolet radiation.
Experimental cell research - 1 Apr 2005
Scott Glynis, Jacobs Stacey, Leopardi Sonya, Anthony Frank A, Learn Doug, Malaviya Rama, Pentland Alice
Abstract excerpt
Prostaglandins are potent lipid hormones that activate multiple signaling pathways resulting in regulation of cellular growth, differentiation, and apoptosis. In the skin, prostaglandins are rapidly released by keratinocytes following ultraviolet radiation and are chronically present in inflammatory skin lesions. We have shown previously that melanocytes, which provide photoprotection to keratinocytes through the...
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