Article
Cytokine polymorphisms in Th1/Th2 pathway genes, body mass index, and risk of non-Hodgkin lymphoma.
Blood - 13 Jan 2011
Chen Yingtai, Zheng Tongzhang, Lan Qing, Foss Francine, Kim Christopher, Chen Xuezhong, Dai Min, Li Yumin, Holford Theodore, Leaderer Brian, Boyle Peter, Chanock Stephen J, Rothman Nathaniel, Zhang Yawei
Abstract excerpt
We conducted a population-based, case-control study in Connecticut women to test the hypothesis that genetic variations in Th1 and Th2 cytokine genes modify the relationship between body mass index (BMI) and risk of non-Hodgkin lymphoma (NHL). Compared with those with BMI less than 25 kg/m(2), women with BMI more than or equal to 25 kg/m(2) had 50% to 90% increased risk of NHL among women who carried IFNGR2...
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