Article
Chromosomal variation in lymphoblastoid cell lines.
Human mutation - 1 Jul 2012
Shirley Matthew D, Baugher Joseph D, Stevens Eric L, Tang Zhenya, Gerry Norman, Beiswanger Christine M, Berlin Dorit S, Pevsner Jonathan
Abstract excerpt
Tens of thousands of lymphoblastoid cell lines (LCLs) have been established by the research community, providing nearly unlimited source material from samples of interest. LCLs are used to address questions in population genomics, mechanisms of disease, and pharmacogenomics. Thus, it is of fundamental importance to define the extent of chromosomal variation in LCLs. We measured variation in genotype and copy...
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