Article
Recognition of overlapping nucleotides by AraC and the sigma subunit of RNA polymerase.
Journal of bacteriology - 1 Sept 2000
Dhiman A, Schleif R
Abstract excerpt
The Escherichia coli promoter p(BAD), under the control of the AraC protein, drives the expression of mRNA encoding the AraB, AraA, and AraD gene products of the arabinose operon. The binding site of AraC at p(BAD) overlaps the RNA polymerase -35 recognition region by 4 bases, leaving 2 bases of the region not contacted by AraC. This overlap raises the question of whether AraC substitutes for the sigma subunit of...
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