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Article

Strain-specific modifier genes governing craniofacial phenotypes.

Birth defects research. Part A, Clinical and molecular teratology - 1 Mar 2012

Mukhopadhyay Partha, Brock Guy, Webb Cynthia, Pisano M Michele, Greene Robert M

Abstract excerpt

BACKGROUND: The presence of strain-specific modifier genes is known to modulate the phenotype and pathophysiology of mice harboring genetically engineered mutations. Thus, identification of genetic modifier genes is requisite to understanding control of phenotypic expression. c-Ski is a transcriptional regulator. Ski(-/-) mice on a C57BL6J (B6) background exhibit facial clefting, while Ski(-/-) mice on a 129P3...

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Identifiers

PMID: 22371338
DOI: 10.1002/bdra.22890
PMCID: PMC3302963

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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