Genomic consequences of background effects on scalloped mutant expressivity in the wing of Drosophila melanogaster.

doi:10.1534/genetics.108.096453

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Article

Genomic consequences of background effects on scalloped mutant expressivity in the wing of Drosophila melanogaster.

Genetics - 1 Mar 2009

Dworkin Ian, Kennerly Erin, Tack David, Hutchinson Jennifer, Brown Julie, Mahaffey James, Gibson Greg

Abstract excerpt

Genetic background effects contribute to the phenotypic consequences of mutations and are pervasive across all domains of life that have been examined, yet little is known about how they modify genetic systems. In part this is due to the lack of tractable model systems that have been explicitly developed to study the genetic and evolutionary consequences of background effects. In this study we demonstrate that...

Topics

Animals
Drosophila Proteins
Drosophila melanogaster
Epistasis, Genetic
Gene Expression Regulation
Genetic Linkage
Genetic Variation
Genome, Insect
Genomics
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Nuclear Proteins

Oligonucleotide Array Sequence Analysis

Transcription Factors

Transcription, Genetic

Wings, Animal

Source

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Identifiers

PMID: 19064709
DOI: 10.1534/genetics.108.096453
PMCID: PMC2651043

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