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Article

Phenotypic and molecular analyses of A/WySn mice.

The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association - 1 Sept 2001

Gong S G

Abstract excerpt

OBJECTIVE: Since its first description, the A strain of mice have been utilized extensively as models to study the processes involved in clefting of the midfacial region. Of the A substrains, the A/WySn has a spontaneous rate of clefting of the lip of about 20% to 30%. The A/WySn mouse model was utilized in this study to analyze and compare the phenotypic and molecular changes in the midfacial region of embryos...

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PMID: 11522170
DOI: 10.1597/1545-1569_2001_038_0486_pamaoa_2.0.co_2

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