Article
Association between WDR21A polymorphisms and airway responsiveness to inhaled corticosteroids in asthmatic patients.
Pharmacogenetics and genomics - 1 May 2012
Cho Sung-Hwan, Park Byung-Lae, Shin Seung Woo, Heo Jeong-Seok, Park Jong-Sook, Park Sung Woo, Jang An-Soo, Chung Il Yup, Shin Houng-Doo, Park Choon-Sik
Abstract excerpt
OBJECTIVE: Genetic polymorphism is partially responsible for the wide variation in the response of moderate-to-severe asthmatic patients to inhaled corticosteroids. The goal of the study was to examine polymorphisms in WDR21A, which encodes a putative glucocorticoid receptor (GR)-interacting protein, for their possible association with corticosteroid responsiveness. METHODS: The change in forced expiratory volume...
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