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Article

Association of the glucocorticoid receptor D641V variant with steroid-resistant asthma: a case-control study.

Pharmacogenetics and genomics - 1 Jun 2015

Zhao Feng, Zhou Gang, Ouyang Haifeng, Liu Yingge, Wang Anhui, Cai Lei, Ti Xinyu, Song Liqiang, Shi Jieran, Wu Changgui, Chen Lihua, Roth Michael, Li Zhikui

Abstract excerpt

OBJECTIVES: Several mutations of the glucocorticoid receptor (GR) gene cause malfunction of the protein, resulting in steroid resistance. In diseases other than asthma, the GR variants I559N, D641V, and V729I have been linked to steroid resistance. The aim of this study was to evaluate the link of these GR variants in steroid-resistant (SR) asthma in the Chinese Han population. METHODS: GR polymorphisms were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25815773
DOI: 10.1097/FPC.0000000000000130

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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