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Article

ATP acts as a survival signal and prevents the mineralization of aortic valve.

Journal of molecular and cellular cardiology - 1 May 2012

Côté Nancy, El Husseini Diala, Pépin Andrée, Guauque-Olarte Sandra, Ducharme Valérie, Bouchard-Cannon Pascale, Audet Audrey, Fournier Dominique, Gaudreault Nathalie, Derbali Habib, McKee Marc D, Simard Chantale, Després Jean-Pierre, Pibarot Philippe, Bossé Yohan, Mathieu Patrick

Abstract excerpt

Calcific aortic valve disease (CAVD) is a disorder related to progressive mineralization of valvular tissue that is a leading cause of heart disease. Thus far, there is no medical treatment to prevent the mineralization of aortic valves. It is generally thought that pathologic mineralization is linked to apoptosis of vascular cells. However, the role of apoptosis during mineralization as well as the survival...

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Identifiers

PMID: 22366713
DOI: 10.1016/j.yjmcc.2012.02.003

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ENPP1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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