Article
Array-comparative genomic hybridization reveals loss of SOCS6 is associated with poor prognosis in primary lung squamous cell carcinoma.
PloS one - 1 Jan 2012
Sriram Krishna B, Larsen Jill E, Savarimuthu Francis Santiyagu M, Wright Casey M, Clarke Belinda E, Duhig Edwina E, Brown Kevin M, Hayward Nicholas K, Yang Ian A, Bowman Rayleen V, Fong Kwun M
Abstract excerpt
BACKGROUND: Primary tumor recurrence commonly occurs after surgical resection of lung squamous cell carcinoma (SCC). Little is known about the genes driving SCC recurrence. METHODS: We used array comparative genomic hybridization (aCGH) to identify genes affected by copy number alterations that may be involved in SCC recurrence. Training and test sets of resected primary lung SCC were assembled. aCGH was used to...
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