Article
Genomic profiling of sinonasal squamous cell carcinoma.
Head & neck - 1 Feb 2011
López Fernando, Llorente José L, García-Inclán Cristina, Alonso-Guervós Marta, Cuesta-Albalad Mari Paz, Fresno Manuel Florentino, Alvarez-Marcos César, Suárez Carlos, Hermsen Mario A
Abstract excerpt
BACKGROUND: Sinonasal squamous cell carcinomas (SCCs) are rare tumors with no etiologic link to tobacco and alcohol, as opposed to other SCCs of the head and neck (HNSCC). Little is known about the genetic changes in sinonasal SCC. METHODS: DNA copy number changes of sinonasal SCC were analyzed by multiplex ligation-dependent probe amplification (MLPA) and microarray comparative genomic hybridization (maCGH), and...
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