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Article

ALK7 Promotes Vascular Smooth Muscle Cells Phenotypic Modulation by Negative Regulating PPARγ Expression.

Journal of cardiovascular pharmacology - 1 Aug 2020

Gong Fu-Han, Cheng Wen-Lin, Zhang Quan, Chen Xi-Lu, Cao Jian-Lei, Yang Ting, Song Wen-Hao, Zhao Fang

Abstract excerpt

As a receptor for transforming growth factor-β, nodal and activin, activin receptor-like kinase 7 (ALK7) previously acts as a suppressor of tumorigenesis and metastasis, which has emerged to play a key role in cardiovascular diseases. However, the potential effect and molecular mechanism of ALK7 on vascular smooth muscle cells' (VSMCs) phenotypic modulation have not been investigated. Using cultured mouse VSMCs...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 32467530
DOI: 10.1097/FJC.0000000000000857

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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