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Article

Regulation of smooth muscle cells in development and vascular disease: current therapeutic strategies.

Expert review of cardiovascular therapy - 1 Nov 2006

Cai Xinjiang

Abstract excerpt

Vascular smooth muscle cells (SMCs) exhibit extensive phenotypic diversity and rapid growth during embryonic development, but maintain a quiescent, differentiated state in adult. The pathogenesis of vascular proliferative diseases involves the proliferation and migration of medial vascular SMCs into the vessel intima, possibly reinstating their embryonic gene expression programs. Multiple mitogenic stimuli induce...

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PMID: 17173496
DOI: 10.1586/14779072.4.6.789

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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