Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Comparative analysis of lesion development and intraspinal inflammation in four strains of mice following spinal contusion injury.

The Journal of comparative neurology - 1 Feb 2006

Kigerl Kristina A, McGaughy Violeta M, Popovich Phillip G

Abstract excerpt

Susceptibility to neuroinflammatory disease is influenced in part by genetics. Recent data indicate that survival of traumatized neurons is strain dependent and influenced by polygenic loci that control resistance/susceptibility to experimental autoimmune encephalomyelitis (EAE), a model of CNS autoimmune disease. Here, we describe patterns of neurodegeneration and intraparenchymal inflammation after traumatic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Analysis of Variance
Share to Encephalomyelitis, Autoimmune, Experimental

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fibrosis

Share to Inflammation

Share to Macrophages

Share to Mice, Congenic

Share to Microglia

Share to Spinal Cord Injuries

Source

Open in PubMed Open full text

Identifiers

PMID: 16374800
DOI: 10.1002/cne.20827
PMCID: PMC2655318

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Comparative analysis of lesion development and intraspinal inflammation in four strains of mice following spinal contusion injury.PMID 16374800Read ↗

Inflammation and susceptibility to neurodegeneration: the use of unbiased genetics to decipher critical regulatory pathways.Semantic proximity Read ↗

Deletion of IL-4Rα in the BALB/c mouse is associated with altered lesion topography and susceptibility to experimental autoimmune encephalomyelitis.Semantic proximity Read ↗

Neurodegeneration and glial activation patterns after mechanical nerve injury are differentially regulated by non-MHC genes in congenic inbred rat strainsSemantic proximity Read ↗

Genetic influences on secondary degeneration and wound healing following spinal cord injury in various strains of miceSemantic proximity Read ↗

Differential patterns of spinal cord pathology induced by MP4, MOG peptide 35-55, and PLP peptide 178-191 in C57BL/6 mice.Semantic proximity Read ↗

iNOS-mediated secondary inflammatory response differs between rat strains following experimental brain contusion.Semantic proximity Read ↗

Attenuated neurological deficit, cell death and lesion volume in Fas-mutant mice is associated with altered neuroinflammation following traumatic brain injury.Semantic proximity Read ↗

Glial immune-related pathways mediate effects of closed head traumatic brain injury on behavior and lethality in Drosophila.Semantic proximity Read ↗

Genetic Ablation of Soluble TNF Does Not Affect Lesion Size and Functional Recovery after Moderate Spinal Cord Injury in Mice.Semantic proximity Read ↗

Increased post-traumatic survival of neurons in IL-6-knockout mice on a background of EAE susceptibility.Semantic proximity Read ↗

The role of different strain backgrounds in bacterial endotoxin-mediated sensitization to neonatal hypoxic-ischemic brain damage.Semantic proximity Read ↗

Strain-specific differences in perivascular inflammation in lungs in two murine models of allergic airway inflammation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.