Article
Synaptic dysfunction in Parkinson's disease.
Advances in experimental medicine and biology - 1 Jan 2012
Picconi Barbara, Piccoli Giovanni, Calabresi Paolo
Abstract excerpt
Activity-dependent modifications in synaptic efficacy, such as long-term depression (LTD) and long-term potentiation (LTP), represent key cellular substrates for adaptive motor control and procedural memory. The impairment of these two forms of synaptic plasticity in the nucleus striatum could ac...
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