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Age-Related Changes in the Osteogenic Differentiation Potential of Mouse Bone Marrow Stromal Cells

4 Mar 2008

Abstract excerpt

Age-dependent bone loss has been well documented in both human and animal models. Although the underlying causal mechanisms are probably multifactorial, it has been hypothesized that alterations in progenitor cell number or function are important. Little is known regarding the properties of bone marrow stromal cells (BMSCs) or bone progenitor cells during the aging process, so the question of whether aging alters...

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PMID: 18435580
DOI: 10.1359/jbmr.080304

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