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Article

Association of the CTLA-4 +49A/G polymorphism with rheumatoid arthritis in Chinese Han population.

Molecular biology reports - 1 Mar 2013

Tang Ming-Jie, Zhou Zu-Bin

Abstract excerpt

Cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) is an important molecule in the regulation of T cells, so the CTLA-4 gene has been considered as a strong candidate associated with T cell-mediated autoimmune diseases such as rheumatoid arthritis (RA). CTLA-4 has many variants and polymorphic forms, among which the +49A/G polymorphism, causing a non-synonymous substitution, has been studied most. However,...

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PMID: 23264071
DOI: 10.1007/s11033-012-2349-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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