Article
Association of the CTLA-4 gene with rheumatoid arthritis in Chinese Han population.
European journal of human genetics : EJHG - 1 Jul 2005
Lei Cai, Dongqing Zhang, Yeqing Shi, Oaks Martin K, Lishan Chen, Jianzhong Jin, Jie Qian, Fang Du, Ningli Li, Xinghai Han, Daming Ren
Abstract excerpt
Cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) is important for downregulation of T-cell activation, and CTLA-4 gene polymorphisms have been implicated as risk factors for rheumatoid arthritis (RA). Previous studies of the association between the +49 polymorphism of the CTLA-4 gene in RA have provided conflicting results. In order to determine association of the CTLA-4 gene with RA in Chinese Han...
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