Article
Impact of the deletion of the six mce operons in Mycobacterium smegmatis.
Microbes and infection - 1 Jul 2012
Klepp Laura I, Forrellad Marina A, Osella Ana V, Blanco Federico C, Stella Emma J, Bianco María Verónica, Santangelo María de la Paz, Sassetti Cristopher, Jackson Mary, Cataldi Angel A, Bigi Fabiana, Morbidoni Héctor R
Abstract excerpt
The Mycobacterium smegmatis genome contains six operons designated mce (mammalian cell entry). These operons, which encode membrane and exported proteins, are highly conserved in pathogenic and non-pathogenic mycobacteria. Although the function of the Mce protein family has not yet been established in Mycobacterium smegmatis, the requirement of the mce4 operon for cholesterol utilization and uptake by...
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