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Characterization of Mce4A protein of Mycobacterium tuberculosis: role in invasion and survival

19 Nov 2008

Abstract excerpt

BACKGROUND: The mce4 operon is one of the four homologues of mammalian cell entry (mce) operons of Mycobacterium tuberculosis. The mce4A (Rv3499c) gene within this operon is homologous to mce1A (Rv0169), that has a role in host cell invasion by M. tuberculosis. Our earlier reports show that mce4 operon is expressed during the stationary phase of growth of the bacillus in culture and during the course of infection...

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PMID: 19019220
DOI: 10.1186/1471-2180-8-200

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