Article
Role of osteoglycin in the linkage between muscle and bone.
The Journal of biological chemistry - 6 Apr 2012
Tanaka Ken-ichiro, Matsumoto Erika, Higashimaki Yoshiko, Katagiri Takenobu, Sugimoto Toshitsugu, Seino Susumu, Kaji Hiroshi
Abstract excerpt
The interaction between muscle tissues and bone metabolism is incompletely understood. We hypothesized that there might be some humoral factors that are produced in muscle tissues and exhibit bone anabolic activity. We, therefore, performed comparative DNA microarray analysis between mouse myoblastic C2C12 cells transfected with either stable empty vector or ALK2 (R206H), the mutation that constitutively...
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