Article
The skeletal muscle Wnt pathway may modulate insulin resistance and muscle development in a diet-induced obese rat model.
Obesity (Silver Spring, Md.) - 1 Aug 2012
Zhou Dan, Strakovsky Rita S, Zhang Xiyuan, Pan Yuan-Xiang
Abstract excerpt
The Wnt signaling pathway is involved in lipid metabolism and obesity development. Skeletal muscle, a pivotal tissue for metabolism, is regulated by the Wnt signaling. However, little is known of this pathway's involvement in insulin sensitivity and myogenesis in animals. The current study focuse...
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