Article
Ectopic expression of Wnt10b decreases adiposity and improves glucose homeostasis in obese rats
20 Jun 2007
Abstract excerpt
The Wnt family of secreted glycoproteins had previously been shown to regulate diverse processes during early development. Wnt signaling also plays a key role in the homeostasis of adult tissues maintaining stem cell pluripotency and determining differentiating cell fate. The age-related decrease in Wnt signaling may contribute to increased muscle adiposity and diminished bone strength. In the current study, we...
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