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Article

Irisin stimulates browning of white adipocytes through mitogen-activated protein kinase p38 MAP kinase and ERK MAP kinase signaling.

Diabetes - 1 Feb 2014

Zhang Yuan, Li Rui, Meng Yan, Li Shiwu, Donelan William, Zhao Yan, Qi Lei, Zhang Mingxiang, Wang Xingli, Cui Taixing, Yang Li-Jun, Tang Dongqi

Abstract excerpt

The number and activity of brown adipocytes are linked to the ability of mammals to resist body fat accumulation. In some conditions, certain white adipose tissue (WAT) depots are readily convertible to a ''brown-like'' state, which is associated with weight loss. Irisin, a newly identified hormo...

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Identifiers

PMID: 24150604
DOI: 10.2337/db13-1106
PMCID: PMC13117908

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24150604-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Irisin stimulates browning of white adipocytes through mitogen-activated protein kinase p38 MAP kinase and ERK MAP kinase signaling.PMID 24150604Read ↗

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