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The Role of Neurodevelopmental Pathways in Brain Tumors

27 Apr 2021

Abstract excerpt

Disruptions to developmental cell signaling pathways and transcriptional cascades have been implicated in tumor initiation, maintenance and progression. Resurgence of aberrant neurodevelopmental programs in the context of brain tumors highlights the numerous parallels that exist between developmental and oncologic mechanisms. A deeper understanding of how dysregulated developmental factors contribute to brain...

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PMID: 34012965
DOI: 10.3389/fcell.2021.659055

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