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Article

Molecular Basis of Pediatric Brain Tumors.

Neuromolecular medicine - 1 Sept 2017

Klonou Alexia, Piperi Christina, Gargalionis Antonios N, Papavassiliou Athanasios G

Abstract excerpt

Brain tumors emerge as the second commonest type of pediatric solid tumors following hematologic malignancies. Genomic profiling of low- and high-grade gliomas, ependymomas and medulloblastomas has revealed chromosomal abnormalities and specific gene mutations which have been associated with aberrant activation of crucial signal transduction pathways, including mitogen-activated protein kinase, mammalian target...

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Identifiers

PMID: 28748347
DOI: 10.1007/s12017-017-8455-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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