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MYCN in human development and diseases

31 May 2024

Abstract excerpt

Somatic mutations in MYCN have been identified across various tumors, playing pivotal roles in tumorigenesis, tumor progression, and unfavorable prognoses. Despite its established notoriety as an oncogenic driver, there is a growing interest in exploring the involvement of MYCN in human development. While MYCN variants have traditionally been associated with Feingold syndrome type 1, recent discoveries highlight...

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PMID: 38884091
DOI: 10.3389/fonc.2024.1417607

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