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Article

Budding of retroviruses utilizing divergent L domains requires nucleocapsid.

Journal of virology - 1 Apr 2012

Bello Nana F, Dussupt Vincent, Sette Paola, Rudd Victoria, Nagashima Kunio, Bibollet-Ruche Frederic, Chen Chaoping, Montelaro Ronald C, Hahn Beatrice H, Bouamr Fadila

Abstract excerpt

We recently reported that human immunodeficiency virus type 1 (HIV-1) carrying PTAP and LYPX(n)L L domains ceased budding when the nucleocapsid (NC) domain was mutated, suggesting a role for NC in HIV-1 release. Here we investigated whether NC involvement in virus release is a property specific to HIV-1 or a general requirement of retroviruses. Specifically, we examined a possible role for NC in the budding of...

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Source

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Identifiers

PMID: 22345468
DOI: 10.1128/JVI.07105-11
PMCID: PMC3318634

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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