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Virus Hijacks Host Proteins and Machinery for Assembly and Budding, with HIV-1 as an Example

13 Jul 2022

Abstract excerpt

Viral assembly and budding are the final steps and key determinants of the virus life cycle and are regulated by virus-host interaction. Several viruses are known to use their late assembly (L) domains to hijack host machinery and cellular adaptors to be used for the requirement of virus replication. The L domains are highly conserved short sequences whose mutation or deletion may lead to the accumulation of...

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PMID: 35891508
DOI: 10.3390/v14071528

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