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Article

Polyuridylated mRNA synthesized by a recombinant influenza virus is defective in nuclear export.

Journal of virology - 1 Jan 2000

Poon L L, Fodor E, Brownlee G G

Abstract excerpt

The poly(A) tail of influenza virus mRNA is synthesized by reiterative copying of a U track near the 5' end of the virion RNA (vRNA) template by the viral RNA polymerase. We have engineered a novel influenza A/WSN/33 virus which contains a neuraminidase (NA) vRNA with its U track mutated into an A track. Instead of synthesizing poly(A)-tailed NA mRNA, this novel virus synthesizes poly(U)-tailed NA mRNA. In...

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Identifiers

PMID: 10590131
DOI: 10.1128/jvi.74.1.418-427.2000
PMCID: PMC111553

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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