Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The impact of adhesion peptides within hydrogels on the phenotype and signaling of normal and cancerous mammary epithelial cells.

Biomaterials - 1 May 2012

Weiss Michael S, Bernabé Beatriz Peñalver, Shikanov Ariella, Bluver Dennis A, Mui Michael D, Shin Seungjin, Broadbelt Linda J, Shea Lonnie D

Abstract excerpt

The microenviroment contributes to directing mammary epithelial cell (MEC) development and the progression of breast cancer. Three-dimensional culture models have been used to support formation of structures that display varying degrees of disorganization that parallel the degree of cancer. Synthetic hydrogels were employed to investigate the mechanisms by which specific adhesion signals in the microenvironment...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Adhesion
Share to Cell Survival

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epithelial Cells

Share to Hydrogels

Share to Mammary Glands, Human

Share to Peptides

Share to Polyethylene Glycols

Share to Regression Analysis

Source

Open in PubMed Open full text

Identifiers

PMID: 22341213
DOI: 10.1016/j.biomaterials.2012.01.055
PMCID: PMC3288720

Genes

STAT1
STAT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The impact of adhesion peptides within hydrogels on the phenotype and signaling of normal and cancerous mammary epithelial cells.PMID 22341213Read ↗

Tunable synthetic extracellular matrices to investigate breast cancer response to biophysical and biochemical cuesSemantic proximity Read ↗

Engineered basement membrane mimetic hydrogels to study mammary epithelial morphogenesis and invasionSemantic proximity Read ↗

Mechanotranscriptomic Profiling of Breast Cancer Cells Intravasated from Engineered MicrotumorsSemantic proximity Read ↗

Distinct phenotypes of cancer cells on tissue matrix gel.Semantic proximity Read ↗

To create the correct microenvironment: three-dimensional heterotypic collagen assays for human breast epithelial morphogenesis and neoplasiaSemantic proximity Read ↗

Matrix-bound EGF promotes malignant phenotypes of breast cancer organoids in the biomimetic ECM of alginateSemantic proximity Read ↗

Development and characterization of a recombinant silk network for 3D culture of immortalized and fresh tumor-derived breast cancer cellsSemantic proximity Read ↗

Mechanoregulation of Cancer-Associated Fibroblast Phenotype in Three-Dimensional Interpenetrating Hydrogel NetworksSemantic proximity Read ↗

Structural Cues from the Tissue Microenvironment Are Essential Determinants of the Human Mammary Epithelial Cell PhenotypeSemantic proximity Read ↗

Sp1 mechanotransduction regulates breast cancer cell invasion in response to multiple tumor-mimicking extracellular matrix cuesSemantic proximity Read ↗

A synthetic matrix with independently tunable biochemistry and mechanical properties to study epithelial morphogenesis and EMT in a lung adenocarcinoma model.Semantic proximity Read ↗

Substratum stiffness regulates Erk signaling dynamics through receptor-level controlSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.