Article
Brain-derived neurotrophic factor Val66Met polymorphism and alcohol-related phenotypes.
Progress in neuro-psychopharmacology & biological psychiatry - 10 Jan 2013
Nedic Gordana, Perkovic Matea Nikolac, Sviglin Korona Nenadic, Muck-Seler Dorotea, Borovecki Fran, Pivac Nela
Abstract excerpt
Alcoholism is a chronic psychiatric disorder affecting neural pathways that regulate motivation, stress, reward and arousal. Brain-derived neurotrophic factor (BDNF) regulates mood, response to stress and interacts with neurotransmitters and stress systems involved in reward pathways and addiction. Aim of the study was to evaluate the association between a single nucleotide polymorphism (BDNF Val66Met or rs6265)...
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