Article
B-cell numbers and phenotype at clinical relapse following rituximab therapy differ in SLE patients according to anti-dsDNA antibody levels.
Rheumatology (Oxford, England) - 1 Jul 2012
Lazarus Mark N, Turner-Stokes Tabitha, Chavele Konstantia-Maria, Isenberg David A, Ehrenstein Michael R
Abstract excerpt
OBJECTIVES: To correlate the kinetics of B-cell repopulation with relapse after B-cell depletion therapy in SLE patients and address whether variation in relapse rate, B-cell numbers and phenotype are related to anti-dsDNA antibody levels. METHODS: Sixty-one patients with refractory SLE were trea...
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