Article
B Cell Subsets and Cellular Signatures and Disease Relapse in Lupus Nephritis.
Frontiers in immunology - 1 Jan 2020
Yap Desmond Y H, Yung Susan, Lee Paul, Yam Irene Y L, Tam Cheryl, Tang Colin, Chan Tak Mao
Abstract excerpt
Introduction: Renal relapses adversely affect the long-term outcomes of patients with lupus nephritis (LN), but the pathogenic mechanisms remain elusive. B cell signatures of miR-148a, BACH1, BACH2, and PAX5 expression are relevant to the regulation of B lymphocyte homeostasis. It is unknown whether B cell signature is related to the relapse of LN. Methods: We compared B lymphocyte subsets and cellular signatures...
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