Article
A novel role for histone chaperones CAF-1 and Rtt106p in heterochromatin silencing.
The EMBO journal - 2 May 2007
Huang Shengbing, Zhou Hui, Tarara Jim, Zhang Zhiguo
Abstract excerpt
The histone chaperones CAF-1 and Rtt106p are required for heterochromatin silencing in the yeast Saccharomyces cerevisiae. Although it has been suggested that CAF-1 is involved in the maintenance of heterochromatin silencing, their exact functions during this process are not well understood. Here, we show that CAF-1 and Rtt106p are involved in the early stages of heterochromatin formation. The binding of Sir...
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