Cloning of cDNA and genomic DNA for human cytochrome P‐450<sub>11β</sub>

doi:10.1016/0014-5793(90)81190-y

Article

Cloning of cDNA and genomic DNA for human cytochrome P‐450<sub>11β</sub>

3 Sept 1990

Abstract excerpt

A full-length cDNA clone encoding steroid 11 beta-hydroxylase (P-45011 beta) has been isolated from a cDNA library derived from human adrenal tumor. The insert of the clone contains an open reading frame encoding a protein of 503 amino acid residues together with a 4 bp 5'-untranslated region and a 576 bp 3'-untranslated region to which a poly(A) tract is attached. The promoter region of the P-450(11) beta gene...

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