Article
Genomic analysis of high-risk smoldering multiple myeloma.
Haematologica - 1 Sept 2012
López-Corral Lucía, Mateos María Victoria, Corchete Luis A, Sarasquete María Eugenia, de la Rubia Javier, de Arriba Felipe, Lahuerta Juan-José, García-Sanz Ramón, San Miguel Jesús F, Gutiérrez Norma C
Abstract excerpt
Smoldering myeloma is an asymptomatic plasma cell dyscrasia with a heterogeneous propensity to progress to active myeloma. In order to investigate the biology of smoldering myeloma patients with high risk of progression, we analyzed the genomic characteristics by FISH, SNP-arrays and gene expression profile of a group of patients with high-risk smoldering myeloma included in a multicenter randomized trial....
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