Article
ERCC1 C118T polymorphism has predictive value for platinum-based chemotherapy in patients with late-stage bladder cancer.
Genetics and molecular research : GMR - 23 May 2016
Xu Z C, Cai H Z, Li X, Xu W Z, Xu T, Yu B, Zou Q, Xu L
Abstract excerpt
This study aims to investigate the association between ERCC1 codon C118T polymorphism and the response rate of platinum-based chemotherapy in patients with late-stage bladder cancer. A total of 41 eligible patients histologically confirmed as having stage IV muscle-invasive transitional cell carcinoma of the bladder were treated with platinum-based chemotherapy for 2-6 cycles. The genotypes of patients were...
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