Article
Novel mutants of elongation factor G.
Journal of molecular biology - 20 Oct 1990
Richter Dahlfors A A, Kurland C G
Abstract excerpt
A novel mutant form of elongation factor G (EF-G) in Escherichia coli is described. This variant EF-G restricts reading frame errors by a factor of 2 to 3 in vivo at two different positions in a lacIZ fusion. In addition, a conventional fusidic acid resistant (fusR) mutant of EF-G was compared with the restrictive mutant. Both mutants were characterized in vitro in a steady-state poly(U) translating system. The...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
