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Article

Novel mutants of elongation factor G.

Journal of molecular biology - 20 Oct 1990

Richter Dahlfors A A, Kurland C G

Abstract excerpt

A novel mutant form of elongation factor G (EF-G) in Escherichia coli is described. This variant EF-G restricts reading frame errors by a factor of 2 to 3 in vivo at two different positions in a lacIZ fusion. In addition, a conventional fusidic acid resistant (fusR) mutant of EF-G was compared wi...

Topics

Drug Resistance, Microbial
Escherichia coli
Fusidic Acid
Guanosine Triphosphate
Kinetics
Lac Operon
Mutation
Peptide Elongation Factor G
Peptide Elongation Factors
Protein Biosynthesis
RNA, Messenger
Ribosomes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 2231719
DOI: 10.1016/s0022-2836(05)80167-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2231719-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Novel mutants of elongation factor G.PMID 2231719Read ↗

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In vivo selection of conditional-lethal mutations in the gene encoding elongation factor G of Escherichia coli.Semantic proximity Read ↗

A central interdomain protein joint in elongation factor G regulates antibiotic sensitivity, GTP hydrolysis, and ribosome translocation.Semantic proximity Read ↗

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Recycling of ribosomal complexes stalled at the step of elongation in Escherichia coli.Semantic proximity Read ↗

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The dynamic structure of EF-G studied by fusidic acid resistance and internal revertants.Semantic proximity Read ↗

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