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Article

Staphylococcus aureus elongation factor G--structure and analysis of a target for fusidic acid.

The FEBS journal - 1 Sept 2010

Chen Yang, Koripella Ravi Kiran, Sanyal Suparna, Selmer Maria

Abstract excerpt

Fusidic acid (FA) is a bacteriostatic antibiotic that locks elongation factor G (EF-G) on the ribosome in a post-translocational state. It is used clinically against Gram-positive bacteria such as pathogenic strains of Staphylococcus aureus, but no structural information has been available for EF-G from these species. We have solved the apo crystal structure of EF-G from S. aureus to 1.9 Å resolution. This...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20718859
DOI: 10.1111/j.1742-4658.2010.07780.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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