Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Intravenous fat emulsion as treatment for ivermectin toxicosis in three dogs homozygous for the ABCB1-1Δ gene mutation.

Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001) - 1 Dec 2011

Wright Heather M, Chen Annie V, Talcott Patricia A, Poppenga Robert H, Mealey Katrina L

Abstract excerpt

OBJECTIVE: To describe the outcome of 3 cases of ivermectin toxicosis in dogs homozygous for the ABCB1-1Δ gene mutation treated with intravenous fat emulsion (IFE). SERIES SUMMARY: One Australian Shepherd and 2 Miniature Australian Shepherds were treated for naturally occurring ivermectin toxicosis with IFE. All 3 dogs were homozygous for the ABCB1-1Δ gene mutation. Serum ivermectin concentrations confirmed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to ATP Binding Cassette Transporter, Subfamily B, Member 1
Share to Dog Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to ABCB1 gene

Share to Ivermectin

Share to Mutation

Share to Neurotoxicity Syndromes

Share to Treatment Failure

Source

Identifiers

PMID: 22316260
DOI: 10.1111/j.1476-4431.2011.00687.x

Genes

ABCB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Intravenous fat emulsion as treatment for ivermectin toxicosis in three dogs homozygous for the ABCB1-1Δ gene mutation.PMID 22316260Read ↗

Use of 20% intravenous lipid emulsion for the treatment of loperamide toxicosis in a Collie homozygous for the ABCB1-1∆ mutation.Semantic proximity Read ↗

Clearance of plasma ivermectin with single pass lipid dialysis in 2 dogs.Semantic proximity Read ↗

Vincristine-induced central neurotoxicity in a collie homozygous for the ABCB1Δ mutation.Semantic proximity Read ↗

Neurotoxic effects of ivermectin administration in genetically engineered mice with targeted insertion of the mutated canine ABCB1 gene.Semantic proximity Read ↗

Toxicology of Avermectins and Milbemycins (Macrocyclic Lactones) and the Role of P-Glycoprotein in Dogs and Cats.Semantic proximity Read ↗

Identification of a nonsense mutation in feline ABCB1.Semantic proximity Read ↗

PREVALENCE OF THE ABCB1-1Δ GENE IN NONDOMESTIC SPECIES OF THE CANIDAE FAMILY.Semantic proximity Read ↗

The Effect of the Canine ABCB1-1Δ Mutation on Sedation after Intravenous Administration of Acepromazine.Semantic proximity Read ↗

Breed is associated with the ABCB1-1Δ mutation in Australian dogs.Semantic proximity Read ↗

ABCB1-1 Delta (MDR1-1 Delta) genotype is associated with adverse reactions in dogs treated with milbemycin oxime for generalized demodicosis.Semantic proximity Read ↗

Functional Characterization of the Cat and Dog Wild-Type and Mutant MDR1 Carrier Proteins and Frequency of the MDR1 Gene Mutation in 800 Cats From Germany.Semantic proximity Read ↗

Disease progression and treatment response of idiopathic epilepsy in Australian Shepherd dogs.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.