Article
Identification of a nonsense mutation in feline ABCB1.
Journal of veterinary pharmacology and therapeutics - 1 Oct 2015
Mealey K L, Burke N S
Abstract excerpt
The aim of this study was to sequence all exons of the ABCB1 (MDR1) gene in cats that had experienced adverse reactions to P-glycoprotein substrate drugs (phenotyped cats). Eight phenotyped cats were included in the study consisting of eight cats that experienced central nervous system toxicosis after receiving ivermectin (n = 2), a combination product containing moxidectin and imidacloprid (n = 3), a combination...
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