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Article

Epidemiologic consequences of microvariation in Mycobacterium tuberculosis.

The Journal of infectious diseases - 15 Mar 2012

Mathema Barun, Kurepina Natalia, Yang Guibin, Shashkina Elena, Manca Claudia, Mehaffy Carolina, Bielefeldt-Ohmann Helle, Ahuja Shama, Fallows Dorothy A, Izzo Angelo, Bifani Pablo, Dobos Karen, Kaplan Gilla, Kreiswirth Barry N

Abstract excerpt

BACKGROUND: Evidence from genotype-phenotype studies suggests that genetic diversity in pathogens have clinically relevant manifestations that can impact outcome of infection and epidemiologic success. We studied 5 closely related Mycobacterium tuberculosis strains that collectively caused extensive disease (n = 862), particularly among US-born tuberculosis patients. METHODS: Representative isolates were selected...

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Identifiers

PMID: 22315279
DOI: 10.1093/infdis/jir876
PMCID: PMC3415951

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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