Article
Anti-D in pregnant women with the RHD(IVS3+1G>A)-associated DEL phenotype.
Transfusion - 1 Sept 2012
Gardener Glenn J, Legler Tobias J, Hyett Jonathan A, Liew Yew-Wah, Flower Robert L, Hyland Catherine A
Abstract excerpt
BACKGROUND: Pregnant women with the DEL phenotype appear to be D- by routine serology. Women with DEL phenotypes that show a partial D-like epitope loss may develop anti-D. It has been proposed that this alloantibody could have a deleterious effect with respect to hemolytic disease in the fetus and newborn. CASE REPORTS: Two pregnant women, one in Australia and one in Germany, were serotyped as D- and were...
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