Article
Anti-D immunization by DEL red blood cells.
Transfusion - 1 Apr 2005
Wagner Thomas, Körmöczi Günther F, Buchta Christoph, Vadon Maria, Lanzer Gerhard, Mayr Wolfgang R, Legler Tobias J
Abstract excerpt
BACKGROUND: No data are available on the immunogenicity of extremely weak D variants called DEL. Evaluation of alloanti-D formation in a D- female patient after transfusion of apparently D- blood from an Austrian donor led to discovery of a so far unknown DEL type. STUDY DESIGN AND METHODS: Standard blood group serologic methods were applied. Molecular typing, RHD sequencing, and D epitope mapping was performed...
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