Tracking human migrations by the analysis of the distribution of HLA alleles, lineages and haplotypes in closed and open populations.

doi:10.1098/rstb.2011.0320

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Article

Tracking human migrations by the analysis of the distribution of HLA alleles, lineages and haplotypes in closed and open populations.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 19 Mar 2012

Fernandez Vina Marcelo A, Hollenbach Jill A, Lyke Kirsten E, Sztein Marcelo B, Maiers Martin, Klitz William, Cano Pedro, Mack Steven, Single Richard, Brautbar Chaim, Israel Shosahna, Raimondi Eduardo, Khoriaty Evelyne, Inati Adlette, Andreani Marco, Testi Manuela, Moraes Maria Elisa, Thomson Glenys, Stastny Peter, Cao Kai

Abstract excerpt

The human leucocyte antigen (HLA) system shows extensive variation in the number and function of loci and the number of alleles present at any one locus. Allele distribution has been analysed in many populations through the course of several decades, and the implementation of molecular typing has significantly increased the level of diversity revealing that many serotypes have multiple functional variants. While...

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Identifiers

PMID: 22312049
DOI: 10.1098/rstb.2011.0320
PMCID: PMC3267126

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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