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Article

Changes in the expression of plasma proteins associated with thrombosis in BRCA1 mutation carriers.

Journal of cancer research and clinical oncology - 1 May 2012

Custodio Ana, López-Farré Antonio J, Zamorano-León José J, Mateos-Cáceres Petra J, Macaya Carlos, Caldés Trinidad, de la Hoya Miguel, Olivera Elena, Puente Javier, Díaz-Rubio Eduardo, Pérez-Segura Pedro

Abstract excerpt

PURPOSE: Although BRCA1 gene mutations have been associated with breast cancer, BRCA1 mutations have been also involved in other functions. Thrombosis and coagulation are novel mechanisms recently associated with cancer. The aims of the present study were (a) to evaluate, using proteomics, if BRCA1 mutation carriers have a different plasma proteins expression related to thrombosis and coagulation profile than...

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Source

Identifiers

PMID: 22311183
DOI: 10.1007/s00432-012-1161-y

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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