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Article

Genetic variations in SREBP-1 and LXRα are not directly associated to PCOS but contribute to the physiological specifics of the syndrome.

Molecular biology reports - 1 Jun 2012

Knebel Birgit, Janssen Onno E, Hahn Susanne, Jacob Sylvia, Nitzgen Ulrike, Haas Jutta, Muller-Wieland Dirk, Kotzka Jorg

Abstract excerpt

The polycystic ovary syndrome (PCOS) is a complex endocrine-metabolic disorder consisting of reproductive disturbances associated with all aspects of the metabolic syndrome and genetic components in the pathology of this complex disease is very likely. Accordingly, variations in single genes might affect specific features of PCOS and thereby help to define different subgroups. SREBP-1 or LXRα have been shown to...

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PMID: 22311022
DOI: 10.1007/s11033-012-1508-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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